Home > Analyzers >

GE Biacore 3000 SPR Biomolecular Interaction Analyzer
GE Biacore 3000 SPR Biomolecular Interaction Analyzer
Our Price: $9,995.00

Condition: Fully Recertified and Tested to Perform at Manufacturer Specifications
Warranty: 90-Day Full Parts and Labor (Click for Info)
Typically Ships Within: 6 to 12 Business Days

Request a Formal Quote

Quantity in Stock:

Product Code: GE-BIA3000

Recertification Protocol
Technical Specification Sheet (NEW)

GE Biacore 3000 SPR Biomolecular Interaction Analyzer

The GE Biacore 3000 SPR Biomolecular Interaction Analyzer is an established, label-free system for detailed studies of biomolecular reactions. The Biacore 3000 delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The unique ability to recover and transfer interaction and further characterization makes the system highly applicable to fast identification of unknown interactants. This analyzer is suitable for studying the interactions of proteins, protein conjugates, nucleic acids, lipid micelles, and even larger particles such as viruses and whole cells. Other major applications include measurement of kinetic constants, detection of binding partners and patterns in screening applications, monitoring of enzymatic processes, defining potential drug targets, and more.

The GE Biacore 3000 SPR Biomolecular Interaction Analyzer is designed for real-time biomolecular interaction analysis using surface plasmon resonance (SPR) technology. This technique monitors the formation and dissociation of biomolecular complexes on a sensor surface as the interaction occurs. By covalently attaching one molecule (the ligand) to the surface, the binding of another molecule in a solution (the analyte) with the ligand is followed. Measurements are made under conditions of continuous flow, where the sensor surface forms one wall of the flow cell. The Biacore 3000 measures surface protein concentrations from a few pg/mm^2, and can monitor changes in the surface concentration on a time scale down to 0.1 seconds. This technology allows for determination of binding specificity, kinetics, and concentration with analytes ranging in size from about 150 to 10^6 g/mole (Daltons) or more. Operation of the Biacore 3000 can be preprogrammed for analysis of up to 192 samples ( 2 x 96-well microplates).

The GE Biacore 3000 SPR Biomolecular Interaction Analyzer includes:
  • > Windows Data Station
  • > Biacore 3000 Control Software Installed
  • > Autosampler Rack
  • > Power Cord
  • > Operator's Guide
  • > Full 90 Day Parts and Labor Warranty

GE Biacore 3000 SPR Biomolecular Analyzer Specifications

Detection Unit Specification
Light Source LED

760 nm

Band Width < 5 nm
Refractive Index Range 1.33 - 1.40 (0 - 70,000 RU)
Baseline Drift Typically < ± 0.3 RU/minute
Data Output

One Flow Cell

Two Flow Cells

Four Flow Cells

0.1, 1 or 10 measurements/s (0.1 - 10 Hz)

0.1, 1 or 5 measurements/s (0.1 - 2 Hz)

0.1, 1 or 2 measurements/s (0.1 - 5 Hz)
Noise Typically < 0.3 RU RMS (10 Hz)
< 0.1 RU RMS (1 Hz)
Temperature Range 4°C to 40°C (not lower than 20°C below ambient temperature)
Temperature Stability Better than ± 3 x 10^-3°C/min
Temperature Equilibration Time

After 5°C Step

After 10°C Step

Typically < 60 minutes

Typically < 120 minutes
Molecular Weight Detection > 180 Da (Daltons)
Pump Specification
Flow Rate Range 1 - 100 µl/minute user-controlled
Increment Steps of 1 µl/minute
Flow Rate Accuracy < ± 2%
Flow Rate Precision < ± 1%
Pressure Range < 0.2 MPa
Autosampler Specification
Dispensing Volume Range 5 - 500 µl (including air segment)
Increment Steps of 1 µl
Accuracy < 1% deviation for volumes greater than or equal to 50 µl

50 µl

5 µl

< 0.4% CV

< 2% CV
Carry Over Between Vials Typically < 1 µl without septum
Typically < 0.1 µl with septum
Sample Capacity per Rack


Rack Type A

Rack Type B

Rack Type C

96-well (0.2 ml/well)

5 Vials, diam. 16 mm (4 ml)
12 Vials, diam. 9 mm (1.5 ml)
40 Vials, diam. 7 mm (0.7 ml)

60 Vials, diam. 9 mm (1.5 ml)

24 Vials, diam. 10.8 mm (Eppendorf 1.5/2.0 ml)
Maximum Vial Height 55 mm
Integrated µ-Fluidic Cartridge Specification
Number of Flow Cells 4
Valves Pneumatic Membrane Valves
Injection Volume to Flow Cell 5 - 750 µl, steps of 1 µl
Carry Over from Previous Injection < 0.1%
Sample Loop Capacity 120 µl (maximum injection volume of 100 µl)
General Specification
Ambient Temperature Range 15°C to 35°C
Ambient Humidity 20 to 85% RH
Dimensions (L x W x H) 29.9 x 13.8 x 24 in (760 x 350 x 610 mm)
Weight 110 lbs (50 kg)
Electrical Requirements 100-120V / 220-240V, 47-63 Hz, 580 VA

GE Biacore 3000 SPR Biomolecular Interaction Analyzer Manual

Click Here to View the Technical Specs for the GE Biacore 3000 SPR Analyzer

Why Buy From Marshall Scientific?

Every product we offer undergoes a rigorous inspection process to verify that all manufacturer specifications are met. All of the electronics and boards are tested for proper function, and any necessary preventative maintenance is performed alongside repairs by our industry trained technicians. Our primary goal is to offer products that are as close to new as possible at an affordable price.

All Lab Equipment is Fully Recertified and Tested

Most Pieces Ship within 2 to 5 Business Days

All Products Come with a Standard Warranty

Trained Customer and Technical Support

Industry Leading Overall Customer Satisfaction

Marshall Scientific's Recertification Protocol


Our technicians decontaminate and clean all equipment upon arrival and upon purchase to create a neutral environment for lab use.

Preliminary testing is conducted to identify potential product defects, upon completion, we replace all faulty and/or under-performing parts with original manufacturer parts that perform up to specification.

Any parts known to fail or malfunction from excessive use are removed and replaced to insure the extended lifetime of your equipment.

Any necessary preventative maintenance is performed alongside repairs, so your purchase will be ready to go as soon as it arrives.

All electronics and boards are tested for proper function and response by our industry trained technicians. Any electronic deficiencies detected are immediately repaired.

Final testing cycles ensure your instrument performs fully at manufacturer specifications, guaranteeing you receive a properly working product ready for use.

Once we finish our rigorous testing and decontamination procedures, your order will be packaged to best protect it during shipment and will include delivery insurance.

Stanford University
We love shopping at Marshall Scientific! Great products, prices, and performance. Marshall Scientific provides 'tried and true' equipment at a fraction of original purchase price. I always shop here first!
Meg W. / Stanford University
Easy to find what you need with clear specs, website ordering was simple, equipment arrived quickly, very well packaged and working as expected! I couldn't ask for more, I'll definitely use them again!
A. Bradley / Honeywell
University of Maryland
They do a very high quality job worth every penny they charge. Customer service is fantastic, they can always be reached by phone or email, and the staff are very knowledgeable and ready to help.
Igor P. / University of Maryland
Click Here to View Our Other Testimonials

Share your knowledge of this product. Be the first to write a review »

Browse for more products in the same category as this item: