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Thermo Scientific NanoDrop One Microvolume Spectrophotometer
Wavelength Range 190 to 850 nm
Wavelength Accuracy ± 1 nm
- Acclaro Sample Intelligence Technology identifies contaminants and ensures data integrity
- Extended auto-range pathlength enables accurate readings up to 27,500 ng/µL (dsDNA)
- High-resolution 7-inch touchscreen interface with intuitive standalone operation
- No consumables required thanks to the direct pipetting pedestal design
- Fast 8-second measurement time with auto-measure and preloaded workflows
- Xenon flash lamp and 2048-element CMOS sensor for precise UV-Vis analysis
- Multiple connectivity options including USB, Ethernet, Wi-Fi, and Bluetooth with 32 GB internal memory
The Thermo Scientific NanoDrop One Microvolume Spectrophotometer is an advanced, compact UV-Vis instrument designed to deliver fast, reliable quantification of nucleic acids, proteins, and other biomolecules using as little as 1-2 µL of sample. With its integrated Thermo Scientific Acclaro Sample Intelligence Technology, the NanoDrop One provides enhanced sample analysis through real-time contaminant identification, corrected concentration values, and immediate feedback on sample quality. These capabilities help users make confident decisions before moving to downstream applications. The instrument features a sleek, standalone design with a 7-inch high-definition touchscreen interface, eliminating the need for a connected PC and maximizing bench space efficiency.
The xenon flash lamp and 2048-element CMOS sensor provide fast, accurate results with a spectral resolution of ≤ 1.8 nm and a measurement time of just 8 seconds. Built-in Auto-Measure functionality and pre-programmed applications simplify routine workflows. For data management and transfer, the instrument includes three USB-A ports, Ethernet, Bluetooth, Wi-Fi connectivity, and 32 GB of internal flash memory. The NanoDrop One is the ideal choice for researchers requiring high-performance, intelligent microvolume analysis with the added flexibility of cuvette-based capabilities.
All of our equipment is fully tested to perform at factory
specifications before being shipped.
The Thermo Scientific NanoDrop One Microvolume Spectrophotometer includes:
- > PV-1 Calibration Report
- > Power Cord
- > Full 180 Day Parts and Labor Warranty
Thermo Scientific NanoDrop One Microvolume Spectrophotometer Specifications
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Wavelength Range
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190 to 850 nm
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Wavelength Accuracy
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± 1 nm
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Photometric Range
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0 to 550 A
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Photometric Accuracy
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3% at 0.97 A, 302 nm
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Minimum Sample Size
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1 uL
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Pathlength
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0.030 to 1.0 mm auto-ranging
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Light Source
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Xenon flash lamp
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Detector
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2048-element CMOS linear image sensor
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Resolution (Spectral Bandwidth)
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≤ 1.8 nm (FWHM at Hg 254 nm)
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Lower Limit of Detection
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2.5 ng/uL (dsDNA)
0.15 mg/mL (BSA)
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Maximum Concentration
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27,500 ng/uL (dsDNA)
820 (400) mg/mL (BSA lgG)
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Measurement Time
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8 seconds
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Connectivity
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Three USB-A ports, ethernet, Bluetooth, and Wi-Fi
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Display
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7 inch touchscreen, 1280 x 800 high-definition color display
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Internal Storage
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32 GB flash memory
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Dimensions (W x D x H)
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8 x 10 x 12.7 in. (20 x 25.4 x 32.3 cm)
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Weight
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7.9 lb. (3.6 kg.)
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Electrical Requirements
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12V DC, 12-18W
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- Confirm the power supply and PCB output correct, stable voltages across all required connections
- Inspect the display for any dim or dead pixels; replace affected components to maintain full visual clarity and operational accuracy
- Verify full functionality of all buttons, ensuring precise and responsive input control
- Check the XY assembly for proper movement and alignment; thoroughly clean all railings, removing any debris or contaminants
- Confirm stable software communication and connection between the instrument and PC, addressing any connectivity issues
- Inspect and clean or replace all filters as required to ensure optimal airflow and performance
- Examine internal wiring and electrical connections for any breaks, disconnections, or tears; replace or secure any compromised wiring
- Test the lamp’s full functionality, replacing it if any performance issues, dimming, or faults are detected
- Execute the necessary validation protocol, documenting completion with a date on a calibration/verification certificate
- Perform and verify appropriate updates to the PC operating system for compatibility and security
- Conduct a thorough cosmetic inspection, ensuring all external components meet quality and aesthetic standards
Technician Inspection and Recertification Checklist: Instruments
The Following Checklist Is to Be Performed on All Incoming and Outgoing Pieces of Equipment
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Task
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Completed?
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Remarks?
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Confirm stable, correct voltage outputs from power supply and PCB
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Completed
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Inspect display for dim or dead pixels; replace as needed
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Completed
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Verify functionality of all buttons for precise, responsive control
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Completed
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Check XY assembly for proper movement; clean railings to remove debris
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Completed
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Confirm stable software communication between instrument and PC
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Completed
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Inspect and clean or replace filters to maintain optimal performance
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Completed
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Examine internal wiring for damage; replace or secure compromised connections
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Completed
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Test lamp functionality; replace if dimming or faults are detected
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Completed
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Execute validation protocol and document on calibration/verification certificate
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Completed
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Update PC operating system for compatibility and security
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Completed
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Conduct cosmetic inspection to ensure quality of external components
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Completed
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To View More of Our Recertification Protocol Click Here
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