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Agilent 1260 Infinity I HPLC System
Agilent 1260 Infinity I HPLC System
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Calibration: Agilent 4 Peak Test w/ Lab Advisor Diagnostics Report

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Product Code: AG-1260HPLC

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Technical Specification Sheet (NEW)

Agilent 1260 Infinity I HPLC System

The Agilent 1260 Infinity I HPLC System offers the most flexibility for solvent selection and automation in HPLC method development, research and all HPLC applications requiring continuous access to a wide range of solvent choices. This system is ideally suited for multi-method, high-throughput workflows and offers convenient access to four solvents for isocratic or gradient analysis, for rapid method development and speeding up preparation of mobile phases and flushing the HPLC system.

The Agilent 1260 Infinity HPLC System's quaternary pump is based on a two-channel, dual-plunger in-series design which comprises all essential functions that a solvent delivery system has to fulfill. Metering of solvent and delivery to the high-pressure side are performed by one pump assembly which can generate pressure up to 600 bar. Degassing of the solvents is done in a built-in vacuum degasser integrated into the quaternary pump. The 1260 Infinity Autosampler is designed to offer the well-established flow-through design with variable volume injection and to achieve extremely low carryover, providing increased analysis speed with sensitivity, resolution, and precision. Paired with the autosampler is a thermostatted column compartment and ALS thermostat to serve as a temperature management system providing heating and cooling in order to meet extreme requirements of retention time reproducibility. The featured Diode-Array Detector (DAD) is designed for the highest optical performance, GLP compliance, and easy maintenance. The DAD provides greatly enhanced sensitivity and baseline stability using a cartridge cell system with optofluidic waveguides. This detector provides for a wavelength range of 190 - 640 nm, an 80 Hz data acquisition rate, and fixed 4 nm slit for rapid optimization of sensitivity, linearity, and spectral resolution.

The Agilent 1260 Infinity HPLC System can be fully controlled from the included Agilent ChemStation Workstation Software, which allows for user-friendly operation in data acquisition, analysis, instrument control, automation, and more.

This Agilent system is in excellent condition and will be fully tested to perform at factory specifications before being shipped.

The Agilent 1260 Infinity I HPLC System includes:
  • > G1311B Quaternary Pump (With Built-In Degasser)
  • > G1367E HiP Autosampler (or G1329B Autosampler, please inquire)
  • > G1330B ALS Thermostat
  • > G1316A TCC w/ Switching Valve
  • > G4212B DAD Detector
  • > Windows 10 Professional 64-Bit Data Station with Flatscreen Monitor
  • > ChemStation Version 4.3 Software Installed
  • > All Power Cords
  • > Can/Crossover Cables
  • > Agilent Lan Interface Card Built-In
  • > Solvent Tubing
  • > Capillaries
  • > All Performance Reports and 4 Peak Report
  • > Full 90 Day Parts and Labor Warranty

Below is a List of Diagnostic Tests Performed On This System
G4212B Diode Array Detector Diagnostic Tests:
  • Filter Test: The test moves the filter into the light path and measures the relative absorbance in the filter position.
  • Dark Current Test: The test measures the dark current from the detector optic.
  • Holmium Oxide Test: The test measures the Holmium spectrum from the built-in Holmium filter. The spectrum is evaluated for peaks at different wavelengths.
  • Lamp Intensity Test: The test verifies functionality of the UV lamp at various wavelengths.
  • Wavelength Intensity Test: The test confirms the accuracy of wavelengths measured.
  • Baseline Noise Test: The test measures the amount of baseline noise drift identified by the detector.
G1311B Quaternary Pump Diagnostic Tests:
  • Pressure Test: The pressure test is a quick, built-in test designed to demonstrate the pressure tightness (up to 400 bar) of the system.
  • Leak Test: The leak test is a built-in troubleshooting designed to demonstrate the leak-tightness of the pump.
G1316A Column Compartment Diagnostic Tests:
  • Thermostat Test: Evaluates the cooling and heating performance of the two Peltier elements.
G1367E (or G1329B) Autosampler Diagnostic Tests:
  • Injector Steps: Performs each movement of the sampling sequence under manual control. This is useful for confirming autosampler functionality.
System Tests:
  • 4 Peak Test (Isocratic Standard): Standard test published by Agilent to confirm complete functionality of the 1260 Infinity HPLC System.

Agilent 1260 Infinity I HPLC System Specifications

DAD Detector Specification
Detection Type 1024-element photodiode array
Light Source Deuterium lamp
Wavelength Range 190 - 640 nm
Short Term Noise (ASTM) Single and Multi-Wavelength < ± 3 × 10^-6 AU at 230 nm/4 nm
Drift < 0.5 × 10^-3 AU/hr at 230 nm
Linear Absorbance Range
> 2.0 AU (5%) at 265 nm
Wavelength Accuracy ± 1 nm
Wavelength Bunching 2 - 400 nm
Slit Width Fixed 4 nm slit
Diode Width ~ 0.5 nm
Signal Data Rate 80 Hz
Spectra Data Rate 80 Hz
Flow Cells

Max-Light Cartridge Cell (10 mm, V [σ], 1.0ul), 60 bar (870 psi) pressure maximum

Max-Light Cartridge Cell (60 mm, V [σ], 4.0ul), 60 bar (870 psi) pressure maximum

Max-Light Cartridge Test Cell

Control and Data Evaluation Agilent ChemStation for LC
Analog Outputs

Recorder/integrator: 100 mV or 1 V, output range 0.001 - 2 AU, one output


Controller-area network (CAN), GPIB, RS-232C, APG Remote: ready, start, stop and shut-down signals, LAN

Safety and Maintenance

Extensive diagnostics, error detection, and display (through control module and ChemStation), leak detection, safe leak handling, leak output signal for shutdown of pumping system. Low voltages in major maintenance areas.

GLP Features

Early maintenance feedback (EMF) for continuous tracking of instrument usage in terms of lamp burn time with user-settable limits and feedback messages. Electronic records of maintenance and errors. Verification of wavelength accuracy with built-in holmium oxide filter.

Housing All materials recyclable

Click Here to View More Specifications for the Agilent 1260 Infinity HPLC System

Quaternary Pump Specification
Setable Flow Range 0.001 - 10 mL/min, in 0.001 mL/min increments
Flow Range

0.05 - 10.0 mL/min

Flow Precision < 0.07% RSD or < 0.02 min SD, whatever is greater based on retention time at constant ambient temperature
Flow Accuracy ± 1% or 10 µl/min
Pressure Operating Range 0 - 60 MPa (0 - 600 bar, 0 - 8,700 psi) up to 5 mL/min, 0 - 20 MPa (0 - 200 bar, 0 - 2950 psi) up to 10 mL/min
Pressure Pulsation < 2% amplitude or < 3 bar at 1 mL/min isopropanol, at all pressures > 1 MPa (10 bar, 147 psi)
Composition Range Settable range: 0 - 95% or 5 - 100%
Composition Precision < 0.2 % RSD or < 0.04 min SD
Delay Volume 600 - 900 µl, dependent on back pressure
Autosampler Specification
Injection Range 0.1 - 100 µl in 0.1 µl increments
Precision < 0.25% from 5 - 40µl
< 0.5% from 2 - 5µl
< 0.7% from 1 - 2µl
< 1.5% from 0.5 - 1µl
Pressure Range Up to 600 bar (8,700 psi)
Sample Viscosity Range 0.2 - 5 cp
Sample Capacity 2 x well plates (MTP) + 10 x 2 ml vials
108 x 2 ml vials in 2 x 54 vial plate plus 10 additional 2 ml vials
30 x 6 ml vials in 2 x 15 vial plate
100 Micro vial tray plus 10 additional 2 ml vials
54 Eppendorf tubes (0.5/1.5/2 ml) in 2 x 27 Eppendorf tube plates
Injection Cycle Time Typically < 21 seconds using default conditions and injection volume of 5µl
Carryover Typically < 0.004%
ALS Thermostat Specification
Temperature Range 4°C to 40°C in 1°C increments
Temperature Accuracy at Ambient Temperatures < 25°C and Humidity < 50% 3°C to 8°C at a setpoint of 4°C
Temperature Accuracy at Ambient Temperatures > 30°C and Humidity > 60% 3°C to 9°C at a setpoint of 4°C
Column Compartment Specification
Temperature Range Ambient -10°C to 80°C at flow rates up to 5 mL/min
Temperature Stability ± 0.15°C
Temperature Accuracy ± 0.8°C
Warm-Up/Cool-Down Time 5 minutes from ambient to 40°C
10 minutes from 40°C to 20°C

Computer Specifications


Dell Optiplex 7010 Desktop PC


Intel Core i5-3470 Processor 3.2GHz



Hard Drive

250GB Internal SSD

Operating System

Windows 10 Professional, 64bit

Agilent 1260 Infinity HPLC System Manual

Click Here to View the Technical Specs for the Agilent 1260 Infinity HPLC System

Why Buy From Marshall Scientific?

Every product we offer undergoes a rigorous inspection process to verify that all manufacturer specifications are met. All of the electronics and boards are tested for proper function, and any necessary preventative maintenance is performed alongside repairs by our industry trained technicians. Our primary goal is to offer products that are as close to new as possible at an affordable price.

All Lab Equipment is Fully Recertified and Tested

Most Pieces Ship within 2 to 5 Business Days

All Products Come with a Standard Warranty

Trained Customer and Technical Support

Industry Leading Overall Customer Satisfaction

Marshall Scientific's Recertification Protocol


Our technicians decontaminate and clean all equipment upon arrival and upon purchase to create a neutral environment for lab use.

Preliminary testing is conducted to identify potential product defects, upon completion, we replace all faulty and/or under-performing parts with original manufacturer parts that perform up to specification.

Any parts known to fail or malfunction from excessive use are removed and replaced to insure the extended lifetime of your equipment.

Any necessary preventative maintenance is performed alongside repairs, so your purchase will be ready to go as soon as it arrives.

All electronics and boards are tested for proper function and response by our industry trained technicians. Any electronic deficiencies detected are immediately repaired.

Final testing cycles ensure your instrument performs fully at manufacturer specifications, guaranteeing you receive a properly working product ready for use.

Once we finish our rigorous testing and decontamination procedures, your order will be packaged to best protect it during shipment and will include delivery insurance.

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